Detroit Lions vs Arizona Cardinals preview, Week 5

Week 5Sun, Oct 11 · 4:25 PM

Detroit Lions

Arizona Cardinals

At State Farm Stadium

Lines

Consensus close, 4 books

Spread: DET −5.5
Total: 52.5

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Matchup preview

This season, games before this one · 2026–27 season

Matchup odds

68DET

32ARI

Opened DET 68

From 4 sportsbooks’ moneylines with the vig removed: the market’s view, not a pick.

Prediction markets

Kalshi DET 68% +0.2 pts vs sportsbooks
Polymarket DET 69% +0.4 pts vs sportsbooks

Exchanges trade on their own money and take no vig; bold marks a gap of 2 points or more.

Game information

Kick-off: Sunday, October 11 at 4:25 PM
Stadium: State Farm StadiumGlendale, AZ
Weather at kick-off: The forecast comes a week before kick-off.

Who wins?

DET

Season leaders

ARI

Jared GoffQB77/109, 8 TD, 0 INT
DET802Passing yardsARI652
Jacoby BrissettQB82/117, 4 TD, 1 INT
Jahmyr GibbsRB65 CAR, 4 TD
DET307Rushing yardsARI160
Jeremiyah LoveRB41 CAR, 1 TD
Amon-Ra St. BrownWR23 REC, 5 TD
DET228Receiving yardsARI211
Trey McBrideTE26 REC, 2 TD
Aidan HutchinsonDE3 games
DET4.0SacksARI2.0
Budda BakerS3 games
D.J. ReedCB · Questionable3 games
DET24TacklesARI24
Jack GibbensQuestionable · LB3 games

The teams side by side: Detroit Lions and Arizona Cardinals per game, with league ranks
DET	Stat	ARI
2–1	Record	1–2
Offense
31.0, 3rd in the league	Points scored	18th in the league, 21.0
267.3, 7th in the league	Passing yards	18th in the league, 217.3
120.7, 9th in the league	Rushing yards	26th in the league, 93.0
Defense
31.7, 32nd in the league	Points allowed	24th in the league, 27.0
326.3, 32nd in the league	Passing yards allowed	22nd in the league, 247.0
117.3, 23rd in the league	Rushing yards allowed	26th in the league, 127.7
Ball security and pressure
0.3, 1st in the league	Turnovers	4th in the league, 0.3
2.3, 8th in the league	Takeaways	23rd in the league, 1.3
4.3, 3rd in the league	Sacks	26th in the league, 1.7
2.3, 15th in the league	Sacks taken	11th in the league, 1.7
Efficiency
+0.23 , 2nd in the league	Offense	0.00 , 20th in the league
+0.16 , 30th in the league	Defense	+0.08 , 23rd in the league

Injury report

Detroit Lions

Ben BartchGOut· Foot
Blake MillerOTQuestionable· Knee
Christian IzienSQuestionable
Christian MahoganyGQuestionable· Hip
D.J. ReedCBQuestionable· Ribs
DJ WonnumLBQuestionable
Juice ScruggsGQuestionable
Tate RatledgeGQuestionable· Elbow
Ahmed HassaneinDEInactive
Bishop FitzgeraldSInactive
Devin WhiteLBInactive
Ennis Rakestraw Jr.CBInactive
Jimmy RolderLBInactive
Keith Abney IICBInactive
Mekhi WingoDTInactive
Tyler ConklinTEInactive

10 more on reserve lists

Arizona Cardinals

Dadrion Taylor-DemersonSOut· Back
Cody SimonLBQuestionable
Garrett WilliamsCBQuestionable· Achilles
Hjalte FroholdtCQuestionable
Isaac SeumaloGQuestionable· Shoulder
Isaiah AdamsGQuestionable· Knee
Jack GibbensLBQuestionable· Shoulder
Josh SweatLBQuestionable· Groin
Mack Wilson Sr.LBQuestionable· Thumb
Max MeltonCBQuestionable· Toe
Roy LopezDTQuestionable
Walter Nolen IIIDTQuestionable
Andrew BillingsDTInactive
Carson BeckQBInactive
Josh FryarOTInactive
Reggie VirgilWRInactive

10 more on reserve lists

Recent meetings

Last five games

Detroit Lions: Detroit Lions: last five games
Date	Opponent	Result	Spread	Total
9/27/26	vs NYJ	Won 31–24	−7, push	49.5, went over
9/17/26	@ BUF	Lost 31–41	–	–
9/13/26	vs NO	Won 31–30	–	–
1/4/26	@ CHI	Won 19–16	–	–
12/25/25	@ MIN	Lost 10–23	–	–

Arizona Cardinals: Arizona Cardinals: last five games
Date	Opponent	Result	Spread	Total
9/27/26	@ SF	Lost 30–36	+7.5, covered	48.5, went over
9/20/26	vs SEA	Lost 7–31	–	–
9/13/26	@ LAC	Won 26–14	–	–
1/4/26	@ LAR	Lost 20–37	–	–
12/28/25	@ CIN	Lost 14–37	–	–