Arizona Cardinals vs San Francisco 49ers: player stats (Sep 21, 2025)

Week 3Final

At Levi's Stadium

Score by quarter
Team	Q1	Q2	Q3	Q4	T
ARI	–	3	3	9	15
SF	–	6	–	10	16

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ARI

Game leaders

Passing yards
Arizona Cardinals: Kyler Murray159 YDS22/35, 1 TD, 0 INT
San Francisco 49ers: Mac Jones284 YDS27/41, 1 TD, 1 INT
Rushing yards
Arizona Cardinals: Trey Benson42 YDS10 CAR, 0 TD
San Francisco 49ers: Christian McCaffrey52 YDS17 CAR, 0 TD
Receiving yards
Arizona Cardinals: Marvin Harrison Jr.44 YDS3 REC, 0 TD
San Francisco 49ers: Ricky Pearsall117 YDS8 REC, 0 TD
Tackles
Arizona Cardinals: Mack Wilson Sr.12 TCK6 SOLO, 0 SCK
San Francisco 49ers: Fred Warner11 TCK5 SOLO, 0 SCK

In Week 3, the San Francisco 49ers held off the Arizona Cardinals 16-15 on September 21, 2025 at Levi's Stadium. Mac Jones passed for 284 yards for the San Francisco 49ers, and Kyler Murray had 159 for the Arizona Cardinals.

Scoring plays

Q2

Arizona Cardinals, Field goal · 8:45C.Ryland 34 yard field goal is GOOD, Center-A.Brewer, Holder-B.Gillikin.ARI 3, SF 0
San Francisco 49ers, Field goal · 4:22E.Pineiro 38 yard field goal is GOOD, Center-J.Weeks, Holder-T.Morstead.ARI 3, SF 3
San Francisco 49ers, Field goal · 0:17E.Pineiro 51 yard field goal is GOOD, Center-J.Weeks, Holder-T.Morstead.ARI 3, SF 6

Q3

Arizona Cardinals, Field goal · 6:37C.Ryland 28 yard field goal is GOOD, Center-A.Brewer, Holder-B.Gillikin.ARI 6, SF 6

Q4

San Francisco 49ers, Touchdown · 10:50M.Jones pass short left to K.Juszczyk for 1 yard, TOUCHDOWN [B.Browning]. E.Pineiro extra point is GOOD, Center-J.Weeks, Holder-T.Morstead.ARI 6, SF 13
Arizona Cardinals, Touchdown · 8:37K.Murray pass short right to T.McBride for 1 yard, TOUCHDOWN. C.Ryland extra point is GOOD, Center-A.Brewer, Holder-B.Gillikin.ARI 13, SF 13
Arizona Cardinals, Safety · 3:15(Shotgun) M.Jones sacked at SF 6 for 0 yards (Ma.Wilson).PENALTY on SF-D.Puni, Offensive Holding, 6 yards, enforced in End Zone, SAFETY - No Play.ARI 15, SF 13
San Francisco 49ers, Field goal · 0:00E.Pineiro 35 yard field goal is GOOD, Center-J.Weeks, Holder-T.Morstead.ARI 15, SF 16

Team stats

Team stats: Arizona Cardinals and San Francisco 49ers
ARI	Stat	SF
5-15(better)33%	3rd down efficiency	2-1020%
2-2(better)100%	4th down efficiency	1-250%
15922/35 C/ATT	Passing yards	284(better)27/41 C/ATT
106(better)28 CAR	Rushing yards	7320 CAR
1	Sacks taken	1
0(better)	Turnovers	1

Box score

Arizona Cardinals: Passing

Kyler MurrayQB	22/35	159	1	0	1	82.9

San Francisco 49ers: Passing

Mac JonesQB	27/41	284	1	1	1	83.8

Arizona Cardinals: Rushing

Kyler MurrayQB	6	37	6.2	9
Trey BensonRB	10	42	4.2	29
James ConnerRB	9	22	2.4	9
Greg DortchWR	1	5	5.0	5
Emari DemercadoRB	2	0	0.0	1

San Francisco 49ers: Rushing

Mac JonesQB	1	-1	-1.0	-1
Christian McCaffreyRB	17	52	3.1	15
Brian Robinson Jr.RB	2	22	11.0	19

Arizona Cardinals: Receiving

Trey BensonRB	3	4	9	0	5
James ConnerRB	3	4	15	0	10
Trey McBrideTE	5	8	43	1	17
Greg DortchWR	2	2	3	0	2
Marvin Harrison Jr.WR	3	6	44	0	32
Emari DemercadoRB	0	1	0	0	0
Tip ReimanTE	2	3	8	0	6
Zay JonesWR	2	3	25	0	18
Michael WilsonWR	1	2	5	0	5
Elijah HigginsTE	1	1	7	0	7

San Francisco 49ers: Receiving

Christian McCaffreyRB	10	15	88	0	20
Ricky PearsallWR	8	11	117	0	34
Kendrick BourneWR	4	6	38	0	11
Jake TongesTE	2	3	21	0	11
Skyy MooreWR	1	1	10	0	10
Kyle JuszczykFB	1	1	1	1	1
Marquez Valdes-ScantlingWR	1	1	9	0	9

Arizona Cardinals: Defense

Mack Wilson Sr.LB	12	6	0	1	0	2
Akeem Davis-GaitherLB	8	5	0	0	0	0
Budda BakerS	6	3	0	0	0	0
Jalen ThompsonS	6	4	0	0	0	0
Kei'Trel ClarkCB	5	3	0	0	0	0
Dadrion Taylor-DemersonS	4	4	0	0	1	1
Dalvin TomlinsonDT	3	3	0	1	0	0
Max MeltonCB	3	2	0	0	0	0
Kitan CrawfordS	2	1	0	0	0	0
Zaven CollinsLB	2	0	0	0	0	0
Denzel BurkeCB	2	2	0	0	0	0
Josh SweatLB	2	1	1	1	0	0
Cody SimonLB	2	0	0	0	0	0
Calais CampbellDE	1	1	0	0	0	0
Jordan BurchLB	1	1	0	0	0	0
Dante StillsDT	1	0	0	0	0	0
Simi FehokoWR	1	1	0	0	0	0
Darius RobinsonDE	1	1	0	0	0	0
Baron BrowningLB	1	0	0	0	0	0
Owen PappoeLB	1	0	0	0	0	0
PJ MustipherDT	1	1	0	0	0	1
Anthony GoodlowDE	1	0	0	0	0	0

San Francisco 49ers: Defense

Fred WarnerLB	11	5	0	0	2
Dee WintersLB	8	4	0	0	1
Marques SigleS	7	2	0	0	0
Sam OkuayinonuDT	7	2	0	0	0
Upton StoutCB	5	3	0	0	1
Bryce HuffDE	5	2	1	1	1
Renardo GreenCB	4	1	0	0	0
Ji'Ayir BrownS	4	2	0	0	0
Deommodore LenoirCB	3	3	0	1	0
Jordan ElliottDT	3	1	0	1	0
Jason PinnockS	3	3	0	0	0
Nick BosaDE	2	0	0	0	0
C.J. WestDT	2	1	0	0	0
Luke GiffordLB	2	0	0	0	0
Mykel WilliamsDE	2	2	0	1	0
Kalia DavisDT	2	0	0	0	0
Darrell Luter Jr.CB	2	0	0	0	0
Siran NealS	1	0	0	0	0
Brayden WillisTE	1	0	0	0	0
Tatum BethuneLB	1	1	0	0	0
Chase LucasCB	1	1	0	0	0
Curtis RobinsonLB	1	1	0	0	0
Trent WilliamsOT	1	1	0	0	0

Arizona Cardinals: Kicking

Chad RylandPK	2/3	34	1

San Francisco 49ers: Kicking

Eddy PineiroPK	3/3	51	1

Lines

Consensus close, 11 books

Spread: SF −1.5; ARI covered
Total: 44.5; opened 42.5; Under

BetMGM closed SF −1.5, total 44.5. 10 more books and every move are in Pro

Sportsbook lines are shown as reference data. Keel Stats takes no bets and gives no picks. 21+. Gambling problem? Call 1-800-GAMBLER. Responsible gaming

Play by play

Season series

ARI 0, SF 2

Sep 21 · this gameArizona Cardinals 15, San Francisco 49ers 16
Nov 16San Francisco 49ers 41, Arizona Cardinals 22

Before and after

Arizona Cardinals

San Francisco 49ers

The divisions this week

This week’s games

Mon, Nov 16

8:15 PMChargers vs Ravens Head to head: Chargers vs Ravens

Thu, Nov 19

8:15 PMColts vs Texans Head to head: Colts vs Texans

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