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Newer meeting, Sep 27: ARI 30, SF 36

San Francisco 49ers vs Arizona Cardinals: player stats (Nov 16, 2025)

Week 11Final

San Francisco 49ers 41, Arizona Cardinals 22, Final

San Francisco 49ers
Arizona Cardinals

At State Farm Stadium

Score by quarter
TeamQ1Q2Q3Q4T
SF131210641
ARI73–1222

Head to head: 49ers vs Cardinals, series and next game

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SF

Game leaders

ARI

In Week 11, the San Francisco 49ers beat the Arizona Cardinals 41-22 on November 16, 2025 at State Farm Stadium. Brock Purdy passed for 200 yards for the San Francisco 49ers, and Jacoby Brissett had 452 for the Arizona Cardinals.

Scoring plays

Q1

  1. San Francisco 49ers, Touchdown · 14:44C.McCaffrey right guard for 1 yard, TOUCHDOWN. E.Pineiro extra point is GOOD, Center-J.Weeks, Holder-T.Morstead.SF 7, ARI 0
  2. San Francisco 49ers, Touchdown · 9:51(Shotgun) B.Purdy pass deep right to G.Kittle for 30 yards, TOUCHDOWN [W.Nolen]. E.Pineiro extra point is Blocked (K.Crawford), Center-J.Weeks, Holder-T.Morstead.SF 13, ARI 0
  3. Arizona Cardinals, Touchdown · 4:58J.Fryar reported in as eligible. Z.Knight left tackle for 6 yards, TOUCHDOWN. C.Ryland extra point is GOOD, Center-A.Brewer, Holder-P.O'Donnell.SF 13, ARI 7

Q2

  1. San Francisco 49ers, Touchdown · 13:39B.Purdy pass short left to C.McCaffrey for 9 yards, TOUCHDOWN. E.Pineiro extra point is No Good, Wide Right, Center-J.Weeks, Holder-T.Morstead.SF 19, ARI 7
  2. Arizona Cardinals, Field goal · 6:29C.Ryland 26 yard field goal is GOOD, Center-A.Brewer, Holder-P.O'Donnell.SF 19, ARI 10
  3. San Francisco 49ers, Field goal · 1:01 E.Pineiro 48 yard field goal is GOOD, Center-J.Weeks, Holder-T.Morstead.SF 22, ARI 10
  4. San Francisco 49ers, Field goal · 0:00 E.Pineiro 47 yard field goal is GOOD, Center-J.Weeks, Holder-T.Morstead.SF 25, ARI 10

Q3

  1. San Francisco 49ers, Field goal · 7:27E.Pineiro 47 yard field goal is GOOD, Center-J.Weeks, Holder-T.Morstead.SF 28, ARI 10
  2. San Francisco 49ers, Touchdown · 2:32(Shotgun) B.Purdy pass short left to G.Kittle for 4 yards, TOUCHDOWN. E.Pineiro extra point is GOOD, Center-J.Weeks, Holder-T.Morstead.SF 35, ARI 10

Q4

  1. Arizona Cardinals, Touchdown · 8:28(No Huddle, Shotgun) J.Brissett pass short middle to T.McBride for 10 yards, TOUCHDOWN. TWO-POINT CONVERSION ATTEMPT. Z.Knight rushes left end. ATTEMPT FAILS. ** Injury Update: SF-L.Gifford has returned to the game.SF 35, ARI 16
  2. San Francisco 49ers, Touchdown · 4:44C.McCaffrey right end for 4 yards, TOUCHDOWN. TWO-POINT CONVERSION ATTEMPT. B.Purdy is sacked. ATTEMPT FAILS.SF 41, ARI 16
  3. Arizona Cardinals, Touchdown · 2:43(No Huddle, Shotgun) J.Brissett pass deep left to G.Dortch for 17 yards, TOUCHDOWN. TWO-POINT CONVERSION ATTEMPT. J.Brissett pass to T.McBride is incomplete. ATTEMPT FAILS.SF 41, ARI 22

Team stats

Team stats: San Francisco 49ers and Arizona Cardinals
SFStatARI
3-933%3rd down efficiency6-14(better)43%
0-04th down efficiency0-0
20019/26 C/ATTPassing yards452(better)47/57 C/ATT
95(better)25 CARRushing yards3614 CAR
1Sacks taken0(better)
0(better)Turnovers3

Box score

San Francisco 49ers: Passing
Brock PurdyQB19/26200301133.5
Arizona Cardinals: Passing
Jacoby BrissettQB47/5745222096.8
San Francisco 49ers: Rushing
Brock PurdyQB1-7-7.00-7
Christian McCaffreyRB13816.2220
Brian Robinson Jr.RB8243.007
Mac JonesQB3-3-1.00-1
Arizona Cardinals: Rushing
Jacoby BrissettQB2-2-1.002
Bam KnightRB5244.817
Michael CarterRB263.003
Emari DemercadoRB581.605
San Francisco 49ers: Receiving
Christian McCaffreyRB5640115
Brian Robinson Jr.RB01000
George KittleTE6667230
Jauan JenningsWR4654025
Kyle JuszczykFB2226021
Demarcus RobinsonWR1213013
Ricky PearsallWR12000
Arizona Cardinals: Receiving
Michael WilsonWR1518185034
Trey McBrideTE1011115128
Bam KnightRB4421012
Michael CarterRB572207
Greg DortchWR6666117
Emari DemercadoRB231209
Elijah HigginsTE231106
Xavier WeaverWR231509
Andre BaccelliaWR11505
San Francisco 49ers: Defense
Curtis RobinsonLB1250000
Dee WintersLB1050100
Deommodore LenoirCB740012
Upton StoutCB720000
Ji'Ayir BrownS730000
Nick MartinLB750000
Renardo GreenCB640000
Luke GiffordLB520000
Jason PinnockS530100
Malik MustaphaS410011
C.J. WestDT420100
Tatum BethuneLB300000
Darrell Luter Jr.CB320000
Marques SigleS200000
Kalia DavisDT210000
Sam OkuayinonuDT210000
Jake TongesTE210000
Keion WhiteDE100001
Luke FarrellTE100000
Siran NealS100000
Jordan ElliottDT100000
Alfred CollinsDT100000
Bryce HuffDE100000
Chase LucasCB100000
Jon WeeksLS100000
Arizona Cardinals: Defense
Cody SimonLB1240000
Budda BakerS830000
Michael CarterRB110000
Greg DortchWR110000
Darius RobinsonDE510000
Jalen ThompsonS520001
Akeem Davis-GaitherLB410000
Max MeltonCB420001
Garrett WilliamsCB310001
PJ MustipherDT320000
Zaven CollinsLB220000
Denzel BurkeCB210001
Walter Nolen IIIDT220200
Kei'Trel ClarkCB220000
Calais CampbellDE100000
Dalvin TomlinsonDT100000
Jordan BurchLB100000
Dante StillsDT110000
Josh SweatLB111100
Josiah DeguaraTE100000
Isaiah AdamsG110000
San Francisco 49ers: Kicking
Eddy PineiroPK3/3482
Arizona Cardinals: Kicking
Chad RylandPK1/2261

Lines

Consensus close, 11 books
Spread
SF −3.5
opened SF −1.5
SF covered
Total
48.5
opened 47.5
Over

BetMGM closed SF −3.5, total 48.5. 10 more books and every move are in Pro

Sportsbook lines are shown as reference data. Keel Stats takes no bets and gives no picks. 21+. Gambling problem? Call 1-800-GAMBLER. Responsible gaming

Play by play

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Season series

SF 2, ARI 0
  1. Sep 21Arizona Cardinals 15, San Francisco 49ers 16
  2. Nov 16 · this gameSan Francisco 49ers 41, Arizona Cardinals 22

Before and after

San Francisco 49ers
Arizona Cardinals

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This week’s games

NFL schedule: every team