San Francisco 49ers
NFC West
10–7 427 scored · 365 allowed
The San Francisco 49ers went 10-7 in 2021, scoring 427 points and allowing 365. Their offense ranked 10th in EPA per play (-0.16) and their defense 17th (-0.23). Jimmy Garoppolo led them with 3,810 passing yards, Elijah Mitchell with 963 rushing yards, and Deebo Samuel Sr. with 1,405 receiving yards.
| Week | Opponent | Result |
|---|---|---|
| Week 1 | @ DETDetroit Lions | W 41–33 |
| Week 2 | @ PHIPhiladelphia Eagles | W 17–11 |
| Week 3 | vs GBGreen Bay Packers | L 28–30 |
| Week 4 | vs SEASeattle Seahawks | L 21–28 |
| Week 5 | @ ARIArizona Cardinals | L 10–17 |
| Week 7 | vs INDIndianapolis Colts | L 18–30 |
| Week 8 | @ CHIChicago Bears | W 33–22 |
| Week 9 | vsARIArizona Cardinals | L 17–31 |
| Week 10 | vs LARLos Angeles Rams | W 31–10 |
| Week 11 | @ JAXJacksonville Jaguars | W 30–10 |
| Week 12 | vs MINMinnesota Vikings | W 34–26 |
| Week 13 | @SEASeattle Seahawks | L 23–30 |
| Week 14 | @ CINCincinnati Bengals | W 26–23 |
| Week 15 | vs ATLAtlanta Falcons | W 31–13 |
| Week 16 | @ TENTennessee Titans | L 17–20 |
| Week 17 | vs HOUHouston Texans | W 23–7 |
| Week 18 | @LARLos Angeles Rams | W 27–24 |
| Wild Card | @ DALDallas Cowboys | W 23–17 |
| Divisional | @GBGreen Bay Packers | W 13–10 |
| Conference | @LARLos Angeles Rams | L 17–20 |
Efficiency
Teams| Plays | Offense | Defense |
|---|---|---|
| EPA/play | −0.16 , 10th in the league | −0.23 , 17th in the league |
| Pass | +0.18 , 1st in the league | −0.11 , 16th in the league |
| Run | −0.55 , 27th in the league | −0.39 , 24th in the league |
| Success | 51 | 50 |
Season leaders
Calendar
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| Jimmy GaroppoloQB | 15 | 3810 | 51 | – | – | – | – |
|---|---|---|---|---|---|---|---|
| Trey LanceQuestionableQB | 6 | 603 | 168 | – | – | – | – |
| JaMycal HastyRB | 11 | – | 68 | 157 | 5 | – | – |
| Elijah MitchellRB | 11 | – | 963 | 137 | – | – | – |
| Trenton CannonRB | 9 | – | -1 | – | 8 | – | – |
| Jeff Wilson Jr.RB | 7 | – | 294 | 31 | 1 | – | – |
| Trey SermonInjured reserveRB | 6 | – | 167 | 26 | 2 | – | – |
| Raheem MostertRB | 1 | – | 20 | – | – | – | – |
| Jacques PatrickRB | 1 | – | 12 | – | – | – | – |
| Brian HillRB | 1 | – | – | – | 1 | – | – |
| Kyle JuszczykQuestionableFB | 15 | – | 22 | 296 | 3 | – | – |
| Brandon AiyukWR | 17 | – | 17 | 826 | – | – | – |
| Deebo Samuel Sr.WR | 16 | 24 | 365 | 1405 | 1 | – | – |
| Jauan JenningsQuestionableWR | 13 | – | – | 282 | 1 | – | – |
| Trent SherfieldWR | 12 | – | – | 87 | 4 | – | – |
| Mohamed SanuWR | 8 | – | – | 177 | 1 | – | – |
| Travis BenjaminWR | 5 | – | – | – | 1 | – | – |
| River CracraftWR | 3 | – | – | – | 3 | – | – |
| George KittleQuestionableTE | 14 | – | 20 | 910 | 2 | – | – |
| Charlie WoernerTE | 8 | – | – | 52 | 7 | – | – |
| Ross DwelleyTE | 3 | – | – | 51 | 1 | – | – |
| Trent WilliamsQuestionableOT | 2 | – | – | – | 1 | – | – |
| Mike McGlincheyOT | 1 | – | – | – | 1 | – | – |
| Tom ComptonG | 2 | – | – | – | 1 | – | – |
| Alex MackC | 2 | – | – | – | – | – | – |
| Daniel BrunskillC | 2 | – | – | – | 3 | – | – |
| Nick BosaOutDE | 17 | – | – | – | 52 | 15.5 | – |
| Arden KeyDE | 16 | – | – | – | 22 | 6.5 | – |
| Samson EbukamQuestionableDE | 15 | – | – | – | 38 | 4.5 | – |
| Jordan WillisDE | 7 | – | – | – | 15 | 3 | – |
| Charles OmenihuQuestionableDE | 6 | – | – | – | 6 | – | – |
| Dee FordDE | 3 | – | – | – | 5 | 3 | – |
| Arik ArmsteadDT | 16 | – | – | – | 63 | 6 | – |
| D.J. JonesDT | 16 | – | – | – | 56 | 2 | – |
| Kentavius StreetDT | 14 | – | – | – | 27 | 3 | – |
| Kevin GivensDT | 11 | – | – | – | 17 | – | – |
| Javon KinlawQuestionableDT | 3 | – | – | – | 8 | – | – |
| Zach KerrDT | 2 | – | – | – | 3 | – | – |
| Maurice Hurst IIDT | 2 | – | – | – | 2 | – | – |
| Fred WarnerLB | 16 | – | – | – | 137 | 0.5 | – |
| Azeez Al-ShaairInactiveLB | 13 | – | – | – | 102 | 2 | 1 |
| Demetrius Flannigan-FowlesLB | 12 | – | – | – | 29 | – | – |
| Dre GreenlawQuestionableLB | 3 | – | – | – | 21 | – | 1 |
| Tyrell AdamsLB | 1 | – | – | – | 1 | – | – |
| Mark NzeochaLB | 1 | – | – | – | 2 | – | – |
| Curtis RobinsonLB | 1 | – | – | – | 1 | – | – |
| K'Waun WilliamsCB | 14 | – | – | – | 52 | 1 | 1 |
| Josh NormanCB | 13 | – | – | – | 49 | – | 1 |
| Emmanuel MoseleyCB | 11 | – | – | – | 42 | – | 1 |
| Dontae JohnsonCB | 10 | – | – | – | 30 | – | – |
| Ambry ThomasCB | 9 | – | – | – | 23 | – | 1 |
| Deommodore LenoirCB | 8 | – | – | – | 17 | – | – |
| Dre KirkpatrickCB | 3 | – | – | – | 7 | – | – |
| Jason VerrettCB | 1 | – | – | – | 5 | – | – |
| Darqueze DennardCB | 1 | – | – | – | 1 | – | – |
| Jimmie WardS | 16 | – | – | – | 77 | – | 2 |
| Jaquiski TarttS | 14 | – | – | – | 66 | – | – |
| Marcell HarrisS | 12 | – | – | – | 44 | 1 | 1 |
| Talanoa HufangaS | 12 | – | – | – | 32 | – | – |
| Tavon WilsonS | 4 | – | – | – | 10 | – | – |
| Jarrod WilsonS | 2 | – | – | – | 3 | – | – |
| Tony JeffersonS | 1 | – | – | – | 1 | – | – |
| Mitch WishnowskyP | 16 | – | – | – | 3 | – | – |
| Robbie GouldPK | 13 | – | – | – | – | – | – |
| Joey SlyePK | 3 | – | – | – | – | – | – |