San Francisco 49ers at Arizona Cardinals
Week 18Sun, Jan 10 · 12:00 AM
San Francisco 49ers at Arizona Cardinals, Sun, Jan 10 · 12:00 AM
At State Farm Stadium
Matchup preview
This season, games before this one · 2026–27 season
Matchup odds
No moneylines yet.
Game information
- Kick-off
- Sunday, January 10 at 12:00 AM
- Stadium
- State Farm StadiumGlendale, AZ
- Weather at kick-off
- The forecast comes a week before kick-off.
Who wins?
SFSeason leaders
ARI
SF789Passing yardsARI652
SF166Rushing yardsARI160
SF174Receiving yardsARI211
SF2.0SacksARI2.0
SF33TacklesARI24
| SF | Stat | ARI |
|---|---|---|
| 3–0 | Record | 1–2 |
| Offense | ||
| 32.7, 2nd in the league | Points scored | 18th in the league, 21.0 |
| 263.0, 9th in the league | Passing yards | 18th in the league, 217.3 |
| 136.3, 6th in the league | Rushing yards | 26th in the league, 93.0 |
| Defense | ||
| 16.7, 3rd in the league | Points allowed | 25th in the league, 27.0 |
| 215.0, 10th in the league | Passing yards allowed | 22nd in the league, 247.0 |
| 105.7, 15th in the league | Rushing yards allowed | 26th in the league, 127.7 |
| Ball security and pressure | ||
| 0.7, 5th in the league | Turnovers | 3rd in the league, 0.3 |
| 0.7, 31st in the league | Takeaways | 23rd in the league, 1.3 |
| 2.3, 17th in the league | Sacks | 26th in the league, 1.7 |
| 0.0, 1st in the league | Sacks taken | 11th in the league, 1.7 |
| Efficiency | ||
| +0.16 , 7th in the league | Offense | 0.00 , 19th in the league |
| −0.03 , 12th in the league | Defense | +0.08 , 24th in the league |
Injury report
San Francisco 49ers
- James Thompson Jr.DTOut· Ankle
- Nick BosaDEOut· Calf
- Dre GreenlawLBQuestionable· Quadriceps
- Eddy PineiroPKQuestionable· Illness
- George KittleTEQuestionable· Achilles
- Gracen HaltonDTQuestionable· Ankle
- Jack JonesCBQuestionable· Foot
- Jaden DuggerLBQuestionable
- Kaelon BlackRBQuestionable· Groin
- Keion WhiteDEQuestionable
- KhaDarel HodgeWRQuestionable· Knee
- Khalid KareemDEQuestionable
- Kyle JuszczykFBQuestionable
- Mike EvansWRQuestionable· Ribs
- Romello HeightDEQuestionable
- Trent WilliamsOTQuestionable· Neck
- Enrique Cruz Jr.OTInactive
- Ephesians PrysockCBInactive
- Jordan JamesRBInactive
- Jordan WatkinsWRInactive
- Kurtis RourkeQBInactive
- Tatum BethuneLBInactive
19 more on reserve lists
Arizona Cardinals
- Cody SimonLBQuestionable
- Garrett WilliamsCBQuestionable· Achilles
- Hjalte FroholdtCQuestionable
- Isaac SeumaloGQuestionable· Shoulder
- Isaiah AdamsGQuestionable· Knee
- Jack GibbensLBQuestionable· Shoulder
- Josh SweatLBQuestionable· Groin
- Mack Wilson Sr.LBQuestionable· Thumb
- Max MeltonCBQuestionable· Toe
- Roy LopezDTQuestionable
- Walter Nolen IIIDTQuestionable
- Andrew BillingsDTInactive
- Cameron RobertsonLBInactive
- Carson BeckQBInactive
- Dadrion Taylor-DemersonSInactive
- Josh FryarOTInactive
- Reggie VirgilWRInactive
- Starling Thomas VCBInactive
10 more on reserve lists
Recent meetings
Last five games
| Date | Opponent | Result | Spread | Total |
|---|---|---|---|---|
| 9/27/26 | vs ARI | Won 36–30 | −7.5, did not cover | 48.5, went over |
| 9/20/26 |  vs MIA | Won 35–13 | – | – |
| 9/10/26 |  @ LAR | Won 27–7 | – | – |
| 1/17/26 |  @ SEA | Lost 6–41 | – | – |
| 1/11/26 |  @ PHI | Won 23–19 | – | – |
| Date | Opponent | Result | Spread | Total |
|---|---|---|---|---|
| 9/27/26 | @ SF | Lost 30–36 | +7.5, covered | 48.5, went over |
| 9/20/26 | vs SEA | Lost 7–31 | – | – |
| 9/13/26 |  @ LAC | Won 26–14 | – | – |
| 1/4/26 | @ LAR | Lost 20–37 | – | – |
| 12/28/25 |  @ CIN | Lost 14–37 | – | – |
Standings
NFL standings| Team | W | L | T | PCT | PF | PA |
|---|---|---|---|---|---|---|
| San Francisco | 3 | 0 | 0 | 1.000 | 98 | 50 |
| Seattle | 2 | 1 | 0 | .667 | 75 | 50 |
| Los Angeles | 1 | 2 | 0 | .333 | 61 | 63 |
| Arizona | 1 | 2 | 0 | .333 | 63 | 81 |
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Box score
The box score appears once the game is under way.